Paired-Like Homeodomain Transcription Factor LEUTX

Preferred Label : Paired-Like Homeodomain Transcription Factor LEUTX;

NCIt synonyms : Paired-Like Homeobox Transcription Factor LEUTX; Leucine-Twenty Homeobox; LEUTX; Leucine Twenty Homeobox; PRD-LIKE Homeobox Transcription Factor LEUTX;

NCIt definition : Paired-like homeodomain transcription factor LEUTX (198 aa, 22 kDa) is encoded by the human LEUTX gene. This protein is involved in embryo genome activation (EGA), which is the transition from maternal to zygotic gene transcription.;

NCIt note : Paired-like homeodomain transcription factor LEUTX binds to a 36 bp DNA element containing a 5'-TAATCC-3' sequence motif found in several embryo genome activation (EGA) genes, referred to as EEA motif (EGA-enriched Alu-motif). (Uniprot);

Details

Origin ID

C213506;

OMIM relation
- Leucine twenty homeobox [OMIM gene]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- LEUTX Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_chemical_classification
- Homeobox Family Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Homeo Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Embryogenesis [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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