" /> Allogeneic Anti-HER2 CAR-NK Cells AB-201 - CISMeF





Preferred Label : Allogeneic Anti-HER2 CAR-NK Cells AB-201;

NCIt synonyms : Allogeneic Anti-HER2 CAR-Natural Killer Cells AB-201; Allogeneic Anti-HER2 CAR-NKs AB-201;

NCIt definition : A preparation of allogeneic, off-the-shelf (OTS), natural killer (NK) cells derived from cord blood (CB), ex vivo expanded and genetically modified to express a chimeric antigen receptor (CAR) specific for the tumor-associated antigen (TAA) human epidermal growth factor receptor 2 (HER2; ErbB2; HER-2), with potential immunomodulating and antineoplastic activities. Upon administration, allogeneic anti-HER2 CAR-NK cells AB-201 recognize, bind to and induce selective cytotoxicity in HER2-expressing tumor cells. HER2 is overexpressed in a variety of cancer cell types and is associated with increased tumor cell proliferation.;

Molecule name : AB-201; AB 201;

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31/07/2025


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