Preferred Label : Allogeneic Anti-CD20 CAR T Cells LUCAR-20SP;
NCIt synonyms : Allogeneic Anti-CD20 CAR-T Cells LUCAR-20SP; Allogeneic Anti-CD20 CAR T-cells LUCAR-20SP;
NCIt definition : A preparation of donor-derived T-lymphocytes that have been genetically modified to
express a chimeric antigen receptor (CAR) targeting the tumor-associated antigen (TAA)
cluster of differentiation 20 (CD20), with potential immunostimulating and antineoplastic
activities. Upon administration, allogeneic anti-CD20 CAR T-cells LUCAR-20SP specifically
recognize and kill CD20-expressing tumor cells. CD20, a non-glycosylated cell surface
phosphoprotein, is a B-cell specific cell surface antigen expressed in B-cell lineage
malignancies.;
Molecule name : LUCAR-20SP; LUCAR 20SP;
Origin ID : C212067;
concept_is_in_subset
- has_target
