Organic Cation Transporter

Preferred Label : Organic Cation Transporter;

NCIt synonyms : Organic Cation Transport Protein;

NCIt definition : Organic Cation Transporter proteins carry positively charged chemical substances containing covalently bound carbon atoms through solubility barriers, such as lipid membranes or across epithelial layers. After binding substrate, transmembrane transporters often undergo an energy-dependent conformational change that moves the substrate across the membrane with (symport) or against (antiport) concentration gradients.;

Details

Origin ID

C21204;

UMLS CUI

C1335132;

Automatic exact mappings (from CISMeF team)
- organic cation transport [GO term]
- organic cation transport proteins [MeSH concept]
- organic cation transport proteins [MeSH Descriptor]
Biochemical function of gene products
- Organic Cation/Carnitine Transporter 2 [NCIt concept]
- Solute Carrier Family 22 Member 1 [NCIt concept]
- Solute Carrier Family 22 Member 18 [NCIt concept]
- Solute Carrier Family 22 Member 2 [NCIt concept]
- Solute Carrier Family 22 Member 3 [NCIt concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
gene_product_has_biochemical_function
- Transport Protein [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Ion Transport Process [NCIt concept]
- Transmembrane Transport [NCIt concept]

Keyword's position in hierarchy(ies) :

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