Preferred Label : CDK2 Inhibitor BG-68501;
NCIt definition : An orally bioavailable inhibitor of cyclin-dependent kinase 2 (CDK2), with potential
antineoplastic activity. Upon oral administration, CDK2 inhibitor BG-68501 selectively
targets, binds to and inhibits the activity of CDK2. This may lead to cell cycle arrest,
the induction of apoptosis, and the inhibition of tumor cell proliferation. CDKs are
serine/threonine kinases that are important regulators of cell cycle progression and
cellular proliferation and are frequently overexpressed in tumor cells.;
Molecule name : BG-68501; ENS 791; ENS-791; BG 68501;
Origin ID : C209765;
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