Preferred Label : CAPRIN1 wt Allele;
NCIt synonyms : Cell Cycle Associated Protein 1 wt Allele; p137GPI; Membrane Component, Chromosome 11, Surface Marker 1 Gene; GRIP137; CONDCAC; GPIP137; NEDLAAD; RNG105; GPI-Anchored Membrane Protein, 137-kD Gene; Caprin 1 Gene; GPIAP1; M11S1;
NCIt definition : Human CAPRIN1 wild-type allele is located in the vicinity of 11p13 and is approximately
51 kb in length. This allele, which encodes caprin-1 protein, plays a role in RNA
binding and the formation of cytoplasmic ribonucleoprotein granules, which downregulate
protein translation. Mutation of the gene is associated with both neurodegeneration,
childhood-onset, with cerebellar ataxia and cognitive decline (CONDCAC), and neurodevelopmental
disorder with language impairment, autism and attention deficit-hyperactivity disorder
(NEDLAAD).;
GenBank Accession Number : BC001731;
Origin ID : C209378;
OMIM relation
- concept_is_in_subset
- gene_found_in_organism
- gene_in_chromosomal_location
- gene_plays_role_in_process
