Preferred Label : Anti-mesothelin CAR T-cells UCMYM802;
NCIt synonyms : Anti-mesothelin CAR T Cells UCMYM802; Anti-MSLN CAR-T Cells UCMYM802; Anti-MSLN CAR T-cells UCMYM802;
NCIt definition : A preparation of T-lymphocytes that have been genetically modified to express a chimeric
antigen receptor (CAR) specific for the human tumor-associated antigen (TAA) mesothelin
(MSLN), with potential immunomodulating and antineoplastic activities. Upon administration,
anti-MSLN CAR T-cells UCMYM802 specifically target and kill MSLN-expressing tumor
cells. MSLN, a cell surface glycoprotein involved in cell adhesion, is overexpressed
in a variety of cancer cell types.;
Molecule name : UCMYM-802; UCMYM 802;
Origin ID : C208072;
concept_is_in_subset
- has_target
