" /> Secretogranin-2 - CISMeF





Preferred Label : Secretogranin-2;

NCIt synonyms : SCG2; Chromogranin C; EM66 Precursor; Secretogranin II Precursor; SgII; Secretoneurin Precursor; Secretogranin II; Secretogranin-II;

NCIt definition : Secretogranin-2 (617 aa, 71 kDa) is encoded by the human SCG2 gene. This protein is involved in chemotaxis, apoptosis and both proliferation and migration of endothelial cells.;

NCIt note : The protein is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown. (LocusLink); Secretogranin-2 is a precursor that is cleaved to produce secretoneurin.;

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30/07/2025


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