Secretogranin-1

Preferred Label : Secretogranin-1;

NCIt synonyms : Secretogranin B; CHGB; Secretogranin I; SgI; CgB; Chromogranin B; Chromogranin-B;

NCIt definition : Secretogranin-1 (677 aa, 78 kDa) is encoded by the human CHGB gene. This protein may play a role in the synthesis of biologically active peptides.;

NCIt note : Chromogranin B is a tyrosine-sulfated secretory protein found in a wide variety of peptidergic endocrine cells. Chromogranin functions as a neuroendocrine secretory granule protein which may be the precursor for other biologically active peptides. (LocusLink);

Details

Origin ID

C20684;

UMLS CUI

C1569747;

Currated CISMeF NLP mapping
- chromogranin B [MeSH concept]
- chromogranin b [MeSH Descriptor]
False automatic mappings
- Chromogranin B (substance) [SNOMED CT concept]
- chromogranin B (1-40) [MeSH concept]
- chromogranin B (1-40) [MeSH Supplementary Concept]
- chromogranin B (368-417) [MeSH concept]
- chromogranin B (368-417) [MeSH Supplementary Concept]
OMIM relation
- Chromogranin b [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- CHGB protein, human [MeSH Supplementary Concept]
- CHGB protein, human [MeSH concept]
- Chromogranin B (substance) [SNOMED CT concept]
- chromogranin B [MeSH concept]
- chromogranin b [MeSH Descriptor]
gene_encodes_gene_product
- CHGB Gene [NCIt concept]
- Chromogranin Gene [NCIt concept]
- Peptide Hormone Gene [NCIt concept]
gene_product_has_associated_anatomy
- Monocyte [NCIt concept]
- Neutrophil [NCIt concept]
- Secretory Granule [NCIt concept]
gene_product_has_biochemical_function
- Signaling Protein [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_biomarker_type
- Tumor Marker [NCIt concept]
gene_product_malfunction_associated_with_disease
- Adrenal Gland Pheochromocytoma [NCIt concept]
gene_product_plays_role_in_biological_process
- Intercellular Communication Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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