Preferred Label : Anti-EGFR/Anti-c-Met Monoclonal Antibody FPI-2053;
NCIt synonyms : Anti-EGFR/c-Met Antibody FPI-2053; Anti-EGFR/Anti-c-Met Bispecific Antibody FPI-2053; Anti-EGFR x Anti-c-Met Monoclonal Antibody FPI-2053;
NCIt definition : A humanized bispecific monoclonal antibody targeting epidermal growth factor receptor
(EGFR) and hepatocyte growth factor receptor (HGFR; c-Met), that can potentially be
used as a ligand in radiotherapy. Upon administration, anti-EGFR/anti-c-Met monoclonal
antibody FPI-2053 simultaneously targets and binds to the extracellular domains of
both EGFR and c-Met expressed on cancer cells. EGFR and c-Met, both upregulated or
mutated in a variety of tumor cell types, play key roles in tumor cell proliferation.;
Molecule name : FPI 2053; FPI-2053;
NCI Metathesaurus CUI : CL1928954;
Origin ID : C206443;
chemical_or_drug_has_mechanism_of_action
- concept_is_in_subset
- has_target
