NCIt definition : A preparation of autologous tumor infiltrating lymphocytes (TILs) engineered to express
the cytokine interleukin-7 (IL-7), with potential immunomodulating and antineoplastic
activities. The TILs are isolated from an autologous tumor sample and transduced with
a lentiviral vector to express IL-7. Upon infusion of the autologous IL-7-expressing
TILs ADP-TILIL7 back into the patient, the TILs specifically recognize, target and
kill the patient's tumor cells. IL-7 is a cytokine that promotes the proliferation
and survival of T-cells and may enhance the activity and durability of the TILs.;