NCIt definition : A cell-based vaccine targets tumors expressing the HER2/neu marker. HER-2/neu is a
growth factor receptor, and its overexpression has been associated with a number of
cancers including breast, ovarian, colon and lung cancers. APC8024 comprise of autologous
antigen-presenting peripheral blood mononuclear cells (APCs) that have been exposed
to HER2/neu protein and can be administered to the patient. These cells may stimulate
an antitumor T-cell response to cancer cells expressing HER2/neu. (NCI04);
UNII : J5Z87L8ROA;
CAS number : 845680-07-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 845680-07-1
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