Grainyhead-Like Protein 3 Homolog

Preferred Label : Grainyhead-Like Protein 3 Homolog;

NCIt synonyms : Sister-of-Mammalian Grainyhead; Sister of Mammalian Grainyhead; Transcription Factor CP2-Like 4; Grainyhead Like Transcription Factor 3; GRHL3; Sister of MGR;

NCIt definition : Grainyhead-like protein 3 homolog (626 aa, 70 kDa) is encoded by the human GRHL3 gene. This protein is involved in transcriptional regulation of genes involved in embryonic morphogenesis, including those affecting neurulation and the differentiation of endo- and ecto-dermal epithelia.;

NCIt note : Grainyhead-like protein 3 homolog binds to the consensus DNA sequence 5'-AACCGGTT-3'. (UniProt);

Détails

Origin ID

C205396;

OMIM relation
- Grainyhead-like 3 [OMIM gene]
gene_encodes_gene_product
- GRHL3 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Transcriptional Activation Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Embryogenesis [NCIt concept]
- Histogenic Process [NCIt concept]
- Morphogenesis [NCIt concept]
- Nervous System Development [NCIt concept]
- Transcriptional Regulation [NCIt concept]

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