C-C Motif Chemokine 8

Preferred Label : C-C Motif Chemokine 8;

NCIt synonyms : MCP-2; SCYA8; SCYA10; Monocyte Chemoattractant Protein-2; HC14; CCL8; Small Inducible Cytokine A8; Small-Inducible Cytokine A8; Small Inducible Cytokine-A8; Monocyte Chemotactic Protein 2; Monocyte Chemoattractant Protein 2;

NCIt definition : C-C motif chemokine 8 (99 aa, 11 kDa) is encoded by the human CCL8 gene. This protein plays a role in leukocyte chemotaxis.;

NCIt note : C-C motif chemokine 8 is cleaved into the following product MCP-2(6-76). This processed form inhibits chemotaxis.;

Details

Origin ID

C20479;

UMLS CUI

C0214737;

Currated CISMeF NLP mapping
- CCL8 protein, human [MeSH concept]
- CCL8 protein, human [MeSH Supplementary Concept]
OMIM relation
- Chemokine, CC motif, ligand 8 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- CCL8 protein, human [MeSH concept]
- CCL8 protein, human [MeSH Supplementary Concept]
Validated automatic mappings to NTBT
- chemokine CCL8 [MeSH concept]
- chemokine ccl8 [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CC Cytokine Gene [NCIt concept]
- CCL8 Gene [NCIt concept]
- Cytokine Gene [NCIt concept]
gene_product_has_associated_anatomy
- Central Nervous System [NCIt concept]
- Epithelial Cell [NCIt concept]
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Signaling Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- Chemokine Signaling Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Antiviral Response [NCIt concept]
- Chemotactic Process [NCIt concept]
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Exocytosis [NCIt concept]
- Immunoregulation [NCIt concept]
- Inflammatory Response [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Leukocyte Trafficking [NCIt concept]
- Maturation [NCIt concept]

Keyword's position in hierarchy(ies) :

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