Fibroblast Growth Factor

Preferred Label : Fibroblast Growth Factor;

NCIt synonyms : DNA Synthesis Factor; Endothelial Cell Growth Factor; Fibroblast Growth Regulatory Factor; FGF; ECGF; Fibroblast Growth Factor Family; FGF Family;

NCIt definition : A family of structurally-related growth factors with high affinity for heparin. These proteins modulate cell proliferation, angiogenesis, wound healing, embryogenesis and paracrine signaling pathways. Fibroblast growth factors (FGF) stimulate signal transduction through binding to specific members of the fibroblast growth factor receptors (FGFR) family tyrosine kinases.;

Details

Origin ID

C20426;

UMLS CUI

C0016026;

Currated CISMeF NLP mapping
- fibroblast growth factor [SNOMED Notion]
- fibroblast growth factor (1-10) [MeSH concept]
- fibroblast growth factor (1-10) [MeSH Supplementary Concept]
- fibroblast growth factors [MeSH Descriptor]
- fibroblast growth factors [MeSH concept]
False automatic mappings
- Fibroblast growth factor (substance) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Fibroblast growth factor [LOINC component]
- Fibroblast growth factor (substance) [SNOMED CT concept]
- fibroblast growth factor [SNOMED Notion]
- fibroblast growth factors [MeSH concept]
- fibroblast growth factors [MeSH Descriptor]
gene_encodes_gene_product
- Fibroblast Growth Factor Gene Family [NCIt concept]
- Growth Factor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Heparin Binding Growth Factor [NCIt concept]
gene_product_plays_role_in_biological_process
- Angiogenic Process [NCIt concept]
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Heparin Binding [NCIt concept]
- Receptor Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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