Preferred Label : Gallium Ga 68-DOTA-MGS5;
NCIt synonyms : 68Ga-DOTA-Minigastrin Analog MGS5; 68Ga-DOTA-MGS5; 68Ga-labeled Minigastrin Analogue MGS5;
NCIt definition : A radioconjugate consisting of the minigastrin analog, MGS5, conjugated, via the bifunctional,
macrocyclic chelating agent 1,4,7,10-tetra-azacyclododecane-1,4,7,10-tetra-acetic
acid (DOTA), to the radioisotope gallium Ga 68, with potential use as a tracer for
cholecystokinin receptor subtype 2 (CCK2R)-epressing tumor cells during positron emission
tomography (PET)/computed tomography (CT). Upon intravenous administration, gallium
Ga 68-DOTA-MGS5 targets and binds to tumor cells expressing CCK2R and these cells
can be detected upon PET/CT imaging. CCK2R is expressed on a variety of tumor cell
types, such as medullary thyroid carcinoma (MTC), and gastroenteropancreatic and bronchopulmonary
neuroendocrine tumors (NETs).;
NCI Metathesaurus CUI : CL1926425;
Origin ID : C204176;
UMLS CUI : C5909623;
Semantic type(s)
- concept_is_in_subset
- has_target
