Heparin-Binding Neurotrophic Factor

Preferred Label : Heparin-Binding Neurotrophic Factor;

NCIt synonyms : Heparin Binding Neurotrophic Factor;

NCIt definition : Heparin-Binding Neurotrophic Factors are a family of polypeptide growth factors produced by peripheral target tissues, as well as the nervous system, that block apoptosis and promote neuronal growth, regeneration, survival, and differentiation. Many growth factors appear to temporarily and non-covalently interact with the glycosaminoglycan heparin, which may affect growth factor activity.;

Details

Origin ID

C20393;

UMLS CUI

C3887578;

Automatic exact mappings (from CISMeF team)
- pleiotrophin [MeSH Supplementary Concept]
- pleiotrophin [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- Growth Factor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Heparin Binding Growth Factor [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Heparin Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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