Preferred Label : Androgen Receptor Degrader RO7656594;
NCIt synonyms : AR Degrader RO7656594;
NCIt definition : An orally bioavailable androgen receptor (AR) degrader, with potential antineoplastic
activity. Upon oral administration, AR degrader RO7656594 targets, binds to and degrades
AR, thereby preventing AR-mediated signaling and inhibiting the proliferation of AR-overexpressing
tumor cells. AR, a hormone-regulated transcription factor, plays a key role in tumor
cell proliferation in castration-resistant prostate cancer (CRPC).;
Molecule name : RO 7656594; GDC 2992; GDC-2992; RG-6537; RG 6537; RO-7656594;
Origin ID : C203630;
concept_is_in_subset
- has_target
