NCIt synonyms : Multiple EGF Like Domains 7 Gene; CMS17; LRP-4; SOST2; MEGF7; Low Density Lipoprotein Receptor-Related Protein 4 Gene; LRP10; CLSS; LDL Receptor Related Protein 4 wt Allele; KIAA0816;
NCIt definition : Human LRP4 wild-type allele is located in the vicinity of 11p11.2 and is approximately
62 kb in length. This allele, which encodes low-density lipoprotein receptor-related
protein 4, is involved in the mediation of signaling pathways stimulated by agrin
and sclerostin binding. Mutations in the gene are associated with Cenani-Lenz syndactyly
syndrome, sclerosteosis 2 and congenital myasthenic syndrome 17.;
OMIM relation
