" /> NUDT15 wt Allele - CISMeF





Preferred Label : NUDT15 wt Allele;

NCIt synonyms : Probable 8-Oxo-dGTP Diphosphatase NUDT15 Gene; MTH2; 8-Oxo-dGTPase NUDT15 Gene; FLJ10956; Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 Gene; Nudix Hydrolase 15 wt Allele; NUDT15D; Probable 7,8-Dihydro-8-Oxoguanine Triphosphatase NUDT15 Gene;

NCIt definition : Human NUDT15 wild-type allele is located in the vicinity of 13q14.2 and is approximately 15 kb in length. This allele, which encodes nucleotide triphosphate diphosphatase NUDT15, plays a role in the hydrolysis of nucleoside triphosphates and their oxidized forms. Variant haplotypes of the gene are associated with poor metabolism of thiopurines 2.;

GenBank Accession Number : NM_018283;

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20/05/2024


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