" /> Anti-CD30/CD3 Bispecific Antibody GEN3017 - CISMeF





Preferred Label : Anti-CD30/CD3 Bispecific Antibody GEN3017;

NCIt synonyms : DuoBody GEN3017; DuoBody CD3xCD30 GEN3017; CD30 x CD3 Bispecific Antibody GEN3017; Anti-CD30/Anti-CD3 Bispecific Antibody GEN3017;

NCIt definition : An Fc-silenced immunoglobulin G1 (IgG1) bispecific monoclonal antibody against the tumor-associated antigen (TAA) CD30 (tumor necrosis factor receptor superfamily member 8; TNFRSF8) and T-cell surface antigen CD3, with potential immunostimulating and antineoplastic activities. Upon administration, anti-CD30/CD3 bispecific antibody GEN3017 targets and binds to both CD30 on the surface of tumor cells and CD3 on T-cells. This results in the cross-linking of tumor cells and T-cells, and induces a cytotoxic T-lymphocyte (CTL) response against CD30-expressing tumor cells. CD30, a member of the tumor necrosis factor receptor superfamily, is overexpressed on the surfaces of certain tumor cells.;

Molecule name : GEN-3017; GEN 3017;

NCI Metathesaurus CUI : CL1920443;

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08/05/2025


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" /> Anti-CD30/CD3 Bispecific Antibody GEN3017 - CISMeF





Preferred Label : Anti-CD30/CD3 Bispecific Antibody GEN3017;

NCIt synonyms : DuoBody GEN3017; DuoBody CD3xCD30 GEN3017; CD30 x CD3 Bispecific Antibody GEN3017; Anti-CD30/Anti-CD3 Bispecific Antibody GEN3017;

NCIt definition : An Fc-silenced immunoglobulin G1 (IgG1) bispecific monoclonal antibody against the tumor-associated antigen (TAA) CD30 (tumor necrosis factor receptor superfamily member 8; TNFRSF8) and T-cell surface antigen CD3, with potential immunostimulating and antineoplastic activities. Upon administration, anti-CD30/CD3 bispecific antibody GEN3017 targets and binds to both CD30 on the surface of tumor cells and CD3 on T-cells. This results in the cross-linking of tumor cells and T-cells, and induces a cytotoxic T-lymphocyte (CTL) response against CD30-expressing tumor cells. CD30, a member of the tumor necrosis factor receptor superfamily, is overexpressed on the surfaces of certain tumor cells.;

Molecule name : GEN-3017; GEN 3017;

NCI Metathesaurus CUI : CL1920443;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
08/05/2025


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.