KIR3DL3 wt Allele

Preferred Label : KIR3DL3 wt Allele;

NCIt synonyms : KIR3DL3 Killer-Cell Immunoglobulin-Like Receptor Gene; KIR3DL7; KIR2DL5B; KIR44; Killer Cell Immunoglobulin-Like Receptor, Three Domains, Long Cytoplasmic Tail, 3 Gene; KIRC1; Killer Cell Ig-Like Receptor KIR3DL7 Gene; CD158Z; Killer Cell Immunoglobulin Like Receptor, Three Ig Domains and Long Cytoplasmic Tail 3 wt Allele;

NCIt definition : Human KIR3DL3 wild-type allele is located in the vicinity of 19q13.42 and is approximately 12 kb in length. This allele, which encodes killer cell immunoglobulin-like receptor 3DL3 protein, is involved in the modulation of natural killer cell-mediated cytolysis.;

NCIt note : The KIR3DL3 gene is one of the killer cell immunoglobulin-like receptor (KIR) framework genes (a group that includes KIR3DL3, KIR3DP1, KIR2DL4, KIR3DL2), which are expressed in all haplotypes. The KIR3DL3 gene is also highly polymorphic, most of the variation has been found in exons 3 through 6. (EntrezGene and OMIM);

GenBank Accession Number : AF352324;

Details

Origin ID

C201151;

OMIM relation
- Killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 [OMIM gene]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 19q13.42 [NCIt concept]
gene_is_element_in_pathway
- Antigen Processing and Presentation Pathway [NCIt concept]
- Graft-Versus-Host Disease Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
gene_plays_role_in_process
- Cell-Mediated Cytotoxicity [NCIt concept]
- Immunoregulation [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

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