" /> Autologous Anti-MAGE-A1 TCR-engineered T-cells TSC-204-C0702 - CISMeF





Preferred Label : Autologous Anti-MAGE-A1 TCR-engineered T-cells TSC-204-C0702;

NCIt synonyms : MAGE-A1-specific HLA-C07:02-restricted TCR-engineered T-cells TSC-204-C0702; T-cell Receptor Engineered T-Cells TSC-204-C0702; MAGE-A1-specific TCR-transduced Autologous T-cells TSC-204-C0702; Autologous MAGE-A1-specific HLA-C07:02-restricted TCR-expressing T-lymphocytes TSC-204-C0702; MAGE-A1-specific TCR-transduced Autologous T Cells TSC-204-C0702;

NCIt definition : A preparation of autologous T-lymphocytes that are engineered to express a T-cell receptor (TCR) specific for melanoma-associated antigen A1 (MAGE-A1) presented on human leukocyte antigen (HLA)-C*07:02, with potential immunomodulating and antineoplastic activities. Upon administration, the autologous anti-MAGE-A1 TCR-engineered T-cells TSC-204-C0702 specifically recognize and bind to MAGE-A1 expressed on tumor cells. This may lead to cytotoxic T-lymphocyte (CTL)-mediated elimination of tumor cells expressing MAGE-A1. MAGE-A1 is a tumor-associated antigen (TAA) overexpressed by a variety of cancer cell types.;

Molecule name : TSC 204-C0702; TSC-204-C0702;

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09/05/2024


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