Preferred Label : PSMA-targeting Fluorescent Imaging Agent IS-002;
NCIt synonyms : Fluorophore IS-002; PSMA-targeted Fluorescent Imaging Agent IS-002;
NCIt definition : A near-infrared (NIR) fluorescent imaging agent targeting the tumor-associated antigen
(TAA) prostate-specific membrane antigen (PSMA), that can potentially be used as a
tumor-selective fluorescent imaging agent during NIR fluorescence imaging-guided surgery.
Upon intravenous administration, the PSMA-targeting fluorescent imaging agent IS-002
targets and binds to PSMA on PSMA-expressing tumor cells. Upon fluorescent imaging,
PSMA-expressing tumors can be visualized and identified, and surgically removed. PSMA
is overexpressed by most prostate cancers.;
Molecule name : IS-002; IS 002;
NCI Metathesaurus CUI : CL1915486;
Origin ID : C201117;
UMLS CUI : C5854629;
Semantic type(s)
concept_is_in_subset
has_target