Preferred Label : Hypermethylation;
NCIt definition : Hypermethylation appears to be a controlled, epigenetic, heritable, and aberrant DNA
methylation reaction on gene promoter regions and CpG islands associated with loss
of (e.g., tumor-suppressor) gene function in diverse cellular pathways through transcriptional
silencing by the formation of transcriptionally repressive chromatin.;
Origin ID : C20102;
UMLS CUI : C1512554;
Semantic type(s)
- biological_process_is_part_of_process
- concept_is_in_subset
