" /> Brentuximab - CISMeF





Preferred Label : Brentuximab;

NCIt synonyms : Anti-CD30 Monoclonal Antibody; Monoclonal Antibody SGN-30;

NCIt related terms : SGN-30;

NCIt definition : A genetically-engineered, chimeric mouse-human, anti-CD30 monoclonal antibody with potential antineoplastic activity. Brentuximab specifically binds to the receptor CD-30, a member of the tumor necrosis factor receptor super-family, which may be overexpressed on the surfaces of Hodgkin lymphoma cells and anaplastic-large cell lymphoma cells. After binding to CD30, this agent interferes with the G1 phase of the cell cycle, thereby inducing growth arrest and apoptosis in susceptible tumor cell populations.;

Alternative definition : NCI-GLOSS: A monoclonal antibody that binds to cells that have the CD30 antigen on their surface, including Hodgkin disease cells and cells from anaplastic large cell lymphoma, and cutaneous T-cell lymphoma. SGN-30 is being studied in the treatment of cancer. It is a type of monoclonal antibody.;

UNII : C67ORA155P;

CAS number : 775303-41-8;

Molecule name : SGN-30; CAC-10;

NSC code : 731636;

Codes from synonyms : CDR0000405812;

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06/05/2025


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