NPM1/MLF1 Fusion Gene

Preferred Label : NPM1/MLF1 Fusion Gene;

NCIt synonyms : NPM-MLF1 Fusion Gene; NPM1::MLF1 Fusion Gene; NPM1-MLF1 Fusion Gene;

NCIt definition : A fusion gene that results from a chromosomal translocation t(3;5)(q25;q34) which fuses the first 5 exons of the NPM1 gene in frame with the coding sequence of the MLF1 gene. This fusion is associated with both myelodysplastic syndrome and acute myeloid leukemia.;

NCI Metathesaurus CUI : CL1907460;

Details

Origin ID

C200450;

gene_encodes_gene_product
- NPM1/MLF1 Fusion Protein [NCIt concept]
gene_has_abnormality
- t(3;5)(q25;q34) [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Acute Myeloid Leukemia with NPM1-MLF1 [NCIt concept]
gene_mapped_to_disease
- Acute Myeloid Leukemia with NPM1-MLF1 [NCIt concept]
related_to_genetic_biomarker
- MLF1 Gene [NCIt concept]
- NPM1 Gene [NCIt concept]

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