Autologous Gene-modified PD-1-positive T-lymphocytes ScTIL210

Preferred Label : Autologous Gene-modified PD-1-positive T-lymphocytes ScTIL210;

NCIt synonyms : Autologous Gene-modified PD-1-positive T-cells ScTIL210;

NCIt definition : A preparation of autologous programmed cell death protein 1 (PD-1; PDCD1; CD279)-positive T-lymphocytes transduced with a lentiviral vector encoding for an as of yet undisclosed receptor, with potential immunomodulating activity. Upon administration, autologous gene-modified PD-1-positive T-lymphocytes ScTIL210 may recognize and kill the patient's tumor cells through as of yet not elucidated receptor binding.;

Molecule name : ScTIL-210; ScTIL 210;

NCI Metathesaurus CUI : CL1907010;

Details

Origin ID

C200166;

chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

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