Preferred Label : CDK2 Inhibitor INX-315;
NCIt related terms : INX-315;
NCIt definition : An orally bioavailable small molecule inhibitor of cyclin-dependent kinase 2 (CDK2),
with potential antineoplastic activity. Upon oral administration, CDK2 inhibitor INX-315
selectively targets, binds to and inhibits the activity of CDK2. This may lead to
cell cycle arrest, the induction of apoptosis, and the inhibition of tumor cell proliferation.
CDKs are serine/threonine kinases that are important regulators of cell cycle progression
and cellular proliferation and are frequently overexpressed in tumor cells.;
UNII : 2QD8YT8RWZ;
CAS number : 2745060-92-6;
Molecule name : INX-315; INX 315;
NCI Metathesaurus CUI : CL1907326;
Origin ID : C200051;
UMLS CUI : C5854463;
Semantic type(s)
- concept_is_in_subset
- has_target
