Preferred Label : Polycomb;
NCIt definition : The Drosophila gene Polycomb (Pc) encodes a transcriptional repressor required for
the segment-specific repression of homeotic selector genes by promoting locus-specific
chromatin compaction. Pc may be involved in the stable transmission of a determined
state by its effects on chromatin structure. It contains one chromo domain and interacts
genetically with ph-p, Antp, E(Pc), Pcl, Asx, and many other genes. Similar sequences
have been identified in African clawed frog, Caenorhabditis elegans, Homo sapiens,
and Mus musculus. (from SWISS-PROT P26017, FlyBase 0003042, and NCI);
Origin ID : C19867;
UMLS CUI : C0083956;
Semantic type(s)
- gene_product_has_organism_source
- gene_product_is_physical_part_of
- gene_product_plays_role_in_biological_process
