Preferred Label : Androgen Receptor Degrader AC176;
NCIt synonyms : AR Degrader AC176;
NCIt definition : An orally bioavailable androgen receptor (AR) chimeric degrader, with potential antineoplastic
activity. Upon oral administration, AR degrader AC176 targets and degrades AR, thereby
preventing AR-mediated signaling and inhibiting the proliferation of AR-overexpressing
tumor cells. AR, a hormone-regulated transcription factor, plays a key role in tumor
cell proliferation in castration-resistant prostate cancer (CRPC).;
Molecule name : AC-176; AC0176; AC 176;
NCI Metathesaurus CUI : CL1914087;
Origin ID : C198533;
UMLS CUI : C5787166;
Semantic type(s)
- concept_is_in_subset
- has_target
