Recombinant Interferon Alfa-2b

Preferred Label : Recombinant Interferon Alfa-2b;

NCIt synonyms : Interferon Alpha-2b; Interferon alfa 2b;

NCIt related terms : IFN alpha-2B; Intron A; interferon alfa-2b;

NCIt definition : A non-glycosylated recombinant interferon with antiviral and antineoplastic activities. Alfa interferons bind to specific cell-surface receptors, resulting in the transcription and translation of genes whose protein products mediate antiviral, antiproliferative, anticancer, and immune-modulating effects.;

Alternative definition : NCI-GLOSS: A drug used to treat some infections caused by viruses and several types of cancer. These include hairy cell leukemia, melanoma, and follicular lymphoma. It is a form of interferon alfa (a substance normally made by cells of the immune system) that is made in the laboratory. It is a type of biological response modifier.;

UNII : 43K1W2T1M6;

CAS number : 99210-65-8; 98530-12-2;

Drug name : Heberon Alfa; Viraferon; Alfatronol; Glucoferon; Intron A; Urifron;

Molecule name : Sch 30500;

NSC code : 377523;

Codes from synonyms : CDR0000644330; CDR0000644342; CDR0000644332; CDR0000644333; 275;

Details

Origin ID

C1953;

UMLS CUI

C0021735;

Automatic exact mappings (from CISMeF team)
- interferon-alpha 8 [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- Interferon Alfa-2b [MeSH concept]
- Interferon alfa-2B [SMS substance]
- Interferon alfa-2b [ICD-11 Extension code]
- Interferon alpha-2 [MeSH Descriptor]
- Interferon-alpha2b [MeSH concept]
- Interferon-alpha2b [MeSH Supplementary Concept]
- Product containing interferon alfa-2b (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Interferon Alfa-2b [MeSH concept]
- Interferon alfa-2b (substance) [SNOMED CT concept]
- Interferon alpha-2 [MeSH Descriptor]
- Product containing interferon alfa-2b (medicinal product) [SNOMED CT concept]
- interferon alfa-2b [ATC Code]
Validated automatic mappings to BTNT
- interferon alfa-2b [ATC Code]
chemical_or_drug_affects_gene_product
- Interferon Alpha Receptor Complex [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Cytokine Receptor Activation [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Cytokine Signaling Process [NCIt concept]
- Gene Regulation Process [NCIt concept]
- Immunopotentiation [NCIt concept]
- Inhibition of Cell Proliferation [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
has_target
- Interferon Alpha Receptor Complex [NCIt concept]
is_component_of_chemotherapy_regimen
- CVD-Aldesleukin-Interferon Alfa-2b Regimen [NCIt concept]
- Interferon Alfa-2b/Zidovudine Regimen [NCIt concept]
- Interferon alfa-2b Regimen [NCIt concept]
- Intra-CSF Interferon Alfa-2b Regimen [NCIt concept]
- Intralesional Interferon Alfa-2b Regimen [NCIt concept]

Keyword's position in hierarchy(ies) :

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