NCIt synonyms : Autologous CAR T-cells U87; Autologous CAR T-lymphocytes U87;
NCIt definition : A preparation of autologous T-lymphocytes that have been genetically modified to express
a chimeric antigen receptor (CAR) specific for an as of yet undisclosed tumor-associated
antigen (TAA), with potential immunostimulating and antineoplastic activities. Upon
administration, autologous CAR T cells U87 specifically targets and binds to tumor
cells that express the undisclosed TAA, resulting in tumor cell lysis.;