Preferred Label : Lutetium Lu 177 Ludotadipep;
NCIt synonyms : Lu 177 Ludotadipep; [177Lu] Ludotadipep;
NCIt definition : A radioconjugate composed of ludotadipep, a prostate-specific membrane antigen (PSMA)-targeting
agent, linked to the beta-emitting radioisotope lutetium Lu 177 (177Lu), with potential
antineoplastic activity against PSMA-expressing tumor cells. Upon administration,
lutetium Lu 177 ludotadipep targets and binds to PSMA-expressing tumor cells. Upon
binding, PSMA-expressing tumor cells are destroyed by 177Lu through the specific delivery
of beta particle radiation. PSMA, a tumor-associated antigen (TAA) and type II transmembrane
protein, is expressed on the membrane of prostatic epithelial cells and overexpressed
on prostate tumor cells as well as a variety of other solid tumors.;
NCI Metathesaurus CUI : CL1912840;
Origin ID : C192813;
UMLS CUI : C5785436;
Semantic type(s)
- concept_is_in_subset
- has_target
