Preferred Label : Fluorine F 18 GEH121224;
NCIt synonyms : [18F]GEH121224; [18F]-GEH121224; GEH121224 (18F); 18F-GEH121224; Fluorine F 18-labeled GEH121224;
NCIt definition : A radioconjugate composed of a human epidermal growth factor receptor 2 (HER2; ErbB2;
HER-2)-targeting ligand labeled with the radioisotope fluorine F 18, with potential
use as a tracer for HER2-expressing tumors during positron emission tomography/computed
tomography (PET/CT). Upon administration of fluorine F 18 GEH121224, the HER2-targeting
moiety targets and binds to HER2-expressing tumor cells. Upon binding, HER2-expressing
tumor cells can be detected during PET/CT imaging. HER2, a tumor-associated antigen
(TAA) overexpressed on a variety of tumor cell types, plays an important role in tumor
cell proliferation, differentiation and survival.;
NCI Metathesaurus CUI : CL1912897;
Origin ID : C192746;
UMLS CUI : C5785390;
Semantic type(s)
- concept_is_in_subset
- has_target
