Preferred Label : FGFR Inhibitor ET0111;
NCIt definition : An orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR),
with potential antineoplastic activity. Upon oral administration, FGFR inhibitor ET0111
binds to and inhibits FGFR, which results in the inhibition of FGFR-mediated signal
transduction pathways. This inhibits proliferation in FGFR-overexpressing tumor cells.
FGFR, a family of receptor tyrosine kinases upregulated in many tumor cell types,
plays a key role in cellular proliferation and survival.;
Molecule name : ET 0111; ET-0111;
NCI Metathesaurus CUI : CL1905582;
Origin ID : C192170;
UMLS CUI : C5784956;
Semantic type(s)
- concept_is_in_subset
- has_target
