ALX3 wt Allele

Preferred Label : ALX3 wt Allele;

NCIt synonyms : Frontonasal Dysplasia Gene; FND1; FND; ALX Homeobox 3 wt Allele; Aristaless-Like Homeobox 3 Gene;

NCIt definition : Human ALX3 wild-type allele is located in the vicinity of 1p13.3 and is approximately 11 kb in length. This allele, which encodes homeobox protein aristaless-like 3 protein, is involved in transcriptional regulation and fetal development. Mutation of the gene is associated with frontonasal dysplasia 1 and preferential methylation of the promoter for the gene may be associated with advanced-stage neuroblastoma.;

NCI Metathesaurus CUI : CL1905440;

GenBank Accession Number : AF008203;

Details

Origin ID

C191927;

UMLS CUI

C5780769;

OMIM relation
- Aristaless-like homeobox 3 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 1p13.3 [NCIt concept]
gene_plays_role_in_process
- Cell Differentiation Process [NCIt concept]
- DNA Binding [NCIt concept]
- Developmental Process [NCIt concept]
- Pattern Formation [NCIt concept]
- Skeletal Development [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients