NCIt synonyms : LEC35; My008; Suppressor of Lec15 and Lec35 Glycosylation Mutation Homolog Gene; Mannose-P-Dolichol Utilization Defect 1 wt Allele; HBEBP2BPA; PQLC5; SL15; SLC66A5; CDGIF; Suppressor of Lec15 Gene; PP3958;
NCIt definition : Human MPDU1 wild-type allele is located in the vicinity of 17p13.1 and is approximately
9 kb in length. This allele, which encodes mannose-P-dolichol utilization defect 1
protein, plays a role in the synthesis of mannose-P-dolichol, which is required for
the synthesis of dolichol-linked oligosaccharides, such as glycosylphosphatidylinositols.
Mutation of the gene is associated with congenital disorder of glycosylation type
1f.;