Preferred Label : Tyrosine Phosphorylated STAT5;
NCIt synonyms : pY-STAT5; Phosphotyrosine-STAT5; Tyrosine Phosphorylated-Signal Transducer and Activator of Transcription 5A/5B; Tyrosine Phosphorylated-STAT5; Tyrosine Phosphorylated-Signal Transducer and Activator of Transcription 5;
NCIt definition : A post-translationally modified form of signal transducer and activator of transcription
5 (STAT5) that has been phosphorylated at a tyrosine (Y; Tyr) residue. Phosphorylation
of STAT5A-Y694 or STAT5B-Y699 promotes STAT5 homodimerization. STAT5A or STAT5B homodimers
translocate into the nucleus and induce STAT5-dependent gene expression.;
NCI Metathesaurus CUI : CL1799352;
Origin ID : C190767;
UMLS CUI : C5783918;
Semantic type(s)
- concept_is_in_subset
- related_to_genetic_biomarker
