Phosphorylated-STAT1 Y701

Preferred Label : Phosphorylated-STAT1 Y701;

NCIt synonyms : STAT1 pY701; Phosphorylated-Signal Transducer and Activator of Transcription 1 Y701; Phospho-STAT1 Y701; pY-STAT1; STAT1 (pY701); Phosphorylated-Signal Transducer and Activator of Transcription 1-Alpha/Beta Y701; STAT1 (Phospho-Tyr701); Tyrosine Phosphorylated STAT1; STAT1 Phosphorylated on Tyr701;

NCIt definition : A post-translationally modified form of signal transducer and activator of transcription 1-alpha/beta protein (STAT1) that has been phosphorylated at tyrosine (Y; Tyr) residue 701. Janus kinase (JAK)-mediated phosphorylation of STAT1-Y701 promotes the formation of STAT1 dimers, which translocate into the nucleus and induce STAT1-dependent gene expression.;

NCI Metathesaurus CUI : CL1799351;

Details

Origin ID

C190766;

UMLS CUI

C5783917;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
related_to_genetic_biomarker
- STAT1 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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