" /> Topoisomerase-I Inhibitor - CISMeF





Preferred Label : Topoisomerase-I Inhibitor;

NCIt synonyms : Topoisomerase-I Inhibitors;

NCIt definition : Any substance that inhibits topoisomerase-I, a topoisomerase that relieves torsional stress in a DNA molecule by cutting only one strand of the DNA double helix. Inhibition of topoisomerase-I causes DNA damage, inhibition of DNA replication, and apoptosis.;

ChEBI ID : CHEBI:50276;

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28/07/2025


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