Elasomeran/Davesomeran

Preferred Label : Elasomeran/Davesomeran;

NCIt synonyms : COVID-19 Bivalent Vaccine mRNA-1273.222; Lipid Nanoparticle-encapsulated mRNA-based Original and Omicron BA.4/BA.5 Bivalent SARS-CoV-2 Vaccine mRNA-1273.222; Elasomeran/LNP-encapsulated mRNA-based Omicron BA.4/BA.5 Bivalent SARS-CoV-2 Vaccine mRNA-1273.222; Original/Omicron BA.4/BA.5 Bivalent COVID-19 Booster Vaccine mRNA-1273.222; LNP-encapsulated mRNA-based Original and Omicron BA.4/BA.5 Bivalent SARS-CoV-2 Vaccine mRNA-1273.222;

NCIt related terms : Moderna COVID-19 Vaccine, Bivalent, US;

NCIt definition : A bivalent booster vaccine consisting of elasomeran, a lipid nanoparticle (LNP) encapsulating a messenger RNA (mRNA) encoding the prefusion stabilized spike (S) protein of the SARS-CoV-2 Wuhan-Hu-1 strain (original), and davesomeran, a LNP encapsulating mRNA encoding the prefusion stabilized S-protein of the SARS-CoV-2 Omicron variant lineages BA.4 and BA.5 (Omicron BA.4/BA.5), with potential immunizing activity against SARS-CoV-2. Upon administration of elasomeran/davesomeran, the LNPs bind to the plasma membrane of cells and release the mRNA into the cells. The mRNA is then translated by ribosomes to produce the SARS-CoV-2 S protein. This may activate both humoral and cellular immune responses which may result in protection against SARS-CoV-2 infection.;

Molecule name : mRNA 1273.222; mRNA-1273.222;

NCI Metathesaurus CUI : CL1798634;

Details

Origin ID

C189804;

UMLS CUI

C5783450;

Semantic type(s)
- Immunologic Factor [UMLS semantic type]
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
- SeroNet Authorized Values [NCIt concept]
- SeroNet Study Descriptors [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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