Autologous Tumor-infiltrating Lymphocytes-Central Memory T-cells

Preferred Label : Autologous Tumor-infiltrating Lymphocytes-Central Memory T-cells;

NCIt synonyms : Autologous TIL-TCM Cells; Autologous TIL-TCMs; Autologous Tumor-infiltrating Lymphocytes-Memory T-cells;

NCIt definition : A preparation of autologous ex-vivo expanded central memory T (Tcm) cell-like tumor-infiltrating lymphocytes (TILs) derived from the patient's tumor tissue and peripheral blood, with potential immunostimulatory and antineoplastic activities. Upon isolation and ex-vivo treatment, the therapeutic ex-vivo-treated autologous TIL-Tcm cells, upon reintroduction into the patient, can activate an antitumor immune respone and eradicate tumor cells.;

NCI Metathesaurus CUI : CL1794257;

Details

Origin ID

C189071;

UMLS CUI

C5708224;

Semantic type(s)
- Cell [UMLS semantic type]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]
concept_is_in_subset
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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