Autologous CAR T-Cells RD14-01

Preferred Label : Autologous CAR T-Cells RD14-01;

NCIt synonyms : Autologous CAR-T Cells RD14-01;

NCIt definition : A preparation of autologous T-lymphocytes that are genetically engineered to express a chimeric antigen receptor (CAR) that targets an as of yet unidentified tumor-associated antigen (TAA), with potential immunomodulatory and antineoplastic activities. Upon administration of autologous CAR T-cells RD14-01, the T-cells target, bind to and induce selective cytotoxicity in tumor cells expressing the TAA.;

Molecule name : RD14-01; RD14 01;

NCI Metathesaurus CUI : CL1794274;

Details

Origin ID

C189050;

UMLS CUI

C5706526;

Semantic type(s)
- Cell [UMLS semantic type]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]
concept_is_in_subset
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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