T-cell-redirecting Antibody JNJ-80948543

Preferred Label : T-cell-redirecting Antibody JNJ-80948543;

NCIt definition : A T-cell-redirecting antibody directed against certain tumor-associated antigens (TAAs) on malignant B-lymphocytes and the T-cell surface antigen CD3, with potential immunostimulating and antineoplastic activities. Upon subcutaneous administration, T-cell redirecting antibody JNJ-80948543 binds to CD3 on cytotoxic T-lymphocytes (CTLs) and TAAs on malignant B-cells. This activates and redirects CTLs to malignant B-cells, leading to CTL-mediated killing of the malignant B-cells.;

Molecule name : JNJ 80948543; JNJ-80948543;

NCI Metathesaurus CUI : CL1794080;

Details

Origin ID

C188792;

UMLS CUI

C5706509;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients