Preferred Label : Gallium Ga 68-VMT02;
NCIt synonyms : [68Ga]-VMT02; [68Ga]VMT02;
NCIt definition : A radioconjugate composed of the melanocyte-stimulating hormone receptor (MSHR; melanocortin-1
receptor; MC1R; melanin-activating peptide receptor; melanotropin receptor)-targeting
moiety, VMT02, labeled with the radioisotope gallium Ga 68, with potential imaging
activity using positron emission tomography (PET). Upon administration of gallium
Ga 68-VMT02, VMT02 targets and binds to MC1R-expressing tumor cells. Upon PET imaging,
MC1R-expressing tumor cells can be detected. MC1R, a G protein-coupled receptor expressed
by melanocytes that binds to melanocortins, is involved in regulating mammalian skin
and hair color. It is upregulated on the surface of metastatic melanoma cells.;
NCI Metathesaurus CUI : CL1792790;
Origin ID : C188171;
UMLS CUI : C5707634;
Semantic type(s)
- concept_is_in_subset
- has_target
