" /> IGH/MAFB Fusion Gene - CISMeF





Preferred Label : IGH/MAFB Fusion Gene;

NCIt synonyms : MAFB-IGH; IGH-MAFB; MAFB/IGH Fusion Gene; MAFB-IGH Fusion Gene; IGH-MAFB Fusion Gene; IGH::MAFB Fusion Gene;

NCIt definition : A fusion gene that results from a chromosomal translocation, t(14;20)(q32;q12), which fuses transcriptional enhancers from the immunoglobulin heavy chain (IGH) gene locus with the promoter region of the MAFB gene. This rearrangement is associated with multiple myeloma, monoclonal gammopathy of undetermined significance (MGUS), smoldering myeloma, plasma cell leukemia and plasmacytoma.;

NCIt note : This fusion results in aberrant expression of the transcription factor MafB protein.;

NCI Metathesaurus CUI : CL1792905;

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10/05/2025


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