FGFR3/IGH Fusion Gene

Preferred Label : FGFR3/IGH Fusion Gene;

NCIt synonyms : IGH/FGFR3 Fusion Gene; FGFR3-IGH Fusion Gene; IGH-FGFR3 Fusion Gene; FGFR3-IGH; IGH-FGFR3; FGFR3::IGH Fusion Gene;

NCIt definition : A fusion gene that results from a chromosomal translocation, t(4;14)(p16;q32), which results in promoter exchange between the immunoglobulin heavy chain (IGH) gene locus and the FGFR3 gene. This rearrangement is associated with multiple myeloma.;

NCIt note : This fusion results in overexpression of the fibroblast growth factor receptor 3 protein.;

NCI Metathesaurus CUI : CL1792910;

Details

Origin ID

C188017;

UMLS CUI

C5707525;

Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_has_abnormality
- t(4;14)(p16;q32) [NCIt concept]
genetic_biomarker_related_to
- t(4;14)(p16;q32)(FGFR3/IGH) Fusion Transcript [Identifier] in Blood or Tissue by FISH Nominal [NCIt concept]
related_to_genetic_biomarker
- FGFR3 Gene [NCIt concept]
- Immunoglobulin Heavy Locus [NCIt concept]

Keyword's position in hierarchy(ies) :

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