Personalized Liposomal Neoantigen-based Peptide Vaccine EVX-01

Preferred Label : Personalized Liposomal Neoantigen-based Peptide Vaccine EVX-01;

NCIt synonyms : Liposomal Peptide-based Vaccine EVX-01; Liposomal Peptide Vaccine EVX-01;

NCIt definition : A personalized liposomal peptide vaccine composed of specific cancer neoepitopes, which are highly patient-specific immunogenic tumor associated antigens (TAAs), with potential immunostimulatory and antineoplastic activities. Upon administration of the personalized liposomal neoantigen-based peptide vaccine EVX-01, the neoepitopes induce cytotoxic T-lymphocyte (CTL)-mediated immune responses against tumor cells expressing these specific TAAs.;

Molecule name : EVX 01; EVX-01;

NCI Metathesaurus CUI : CL1792245;

Details

Origin ID

C187302;

UMLS CUI

C5706394;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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