" /> EGFR Inhibitor NRC-2694 Dihydrochloride - CISMeF





Preferred Label : EGFR Inhibitor NRC-2694 Dihydrochloride;

NCIt related terms : NRC-2694 DIHYDROCHLORIDE;

NCIt definition : The dihydrochloride salt form of NRC-2694, an orally bioavailable, small-molecule inhibitor of epidermal growth factor receptor (EGFR), with potential antineoplastic activity. Upon oral administration, EGFR inhibitor NRC-2694 binds to and inhibits EGFR, which prevents EGFR-mediated signaling and leads to cell death in EGFR-expressing tumor cells. EGFR, a receptor tyrosine kinase mutated in many tumor cell types, plays a key role in tumor cell proliferation and tumor vascularization.;

UNII : JRT6MBD7C2;

CAS number : 1172627-00-7;

Molecule name : NRC-2694B;

NCI Metathesaurus CUI : CL1779200;

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08/05/2025


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